{"id":1991,"date":"2017-07-31T20:04:59","date_gmt":"2017-07-31T20:04:59","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/effusions-metastatic-lung-cancer\/"},"modified":"2025-02-10T20:03:08","modified_gmt":"2025-02-10T20:03:08","slug":"effusions-metastatic-lung-cancer","status":"publish","type":"page","link":"https:\/\/stage.cytologystuff.com\/zh-hans\/non-gyn-atlas\/effusions-metastatic-lung-cancer\/","title":{"rendered":"Effusions – Metastatic Lung Cancer"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Effusions – Metastatic Lung Cancer” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

EFFUSIONS – METASTATIC LUNG CANCER<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 80<\/strong>
\nPleural effusion: Adenocarcinoma, lung origin. 20x<\/div>\n<\/div>\n
Figure 80<\/strong>
\nPleural effusion:
\nAdenocarcinoma, lung origin.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 81<\/strong>
\nPleural effusion: Adenocarcinoma, lung origin. 20x<\/div>\n<\/div>\n
Figure 81<\/strong>
\nPleural effusion:
\nAdenocarcinoma, lung origin.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 82<\/strong>
\nPleural effusion: Adenocarcinoma, lung origin. 60x<\/div>\n<\/div>\n
Figure 82<\/strong>
\nPleural effusion:
\nAdenocarcinoma, lung origin.
\n60x<\/div>\n
<\/div>\n

Figures 80-82: Pleural effusion: Adenocarcinoma, lung origin.<\/strong>
\nPhotomicrographs show adenocarcinoma.Often it is easy to distinguish adenocarcinoma from mesothelioma. At times sophisticated technology including electron microscopy and immunohistochemistry may assist in defining a likely primary site. Knowing the patient’s history of malignancy is always the key to identifying metastases.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 83<\/strong>
\nPleural effusion: Moderately differentiated adenocarcinoma, lung origin. 20x<\/div>\n<\/div>\n
Figure 83<\/strong>
\nPleural effusion:
\nModerately differentiated adenocarcinoma, lung origin.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 84<\/strong>
\nPleural effusion: Moderately differentiated adenocarcinoma, lung origin. 60x<\/div>\n<\/div>\n
Figure 84<\/strong>
\nPleural effusion:
\nModerately differentiated adenocarcinoma, lung origin.
\n60x<\/div>\n
<\/div>\n

Figures 83-84: Pleural effusion, moderately differentiated adenocarcinoma, lung origin.<\/strong>
\nNote the papillary glandular arrangements of the tumor cells, prominent nucleoli, vacuolization and mitotic figures. Distinctions from other sources of adenocarcinoma may be impossible.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 85<\/strong>
\nPeritoneal effusion: Adenocarcinoma, lung origin. 20x<\/div>\n<\/div>\n
Figure 85<\/strong>
\nPeritoneal effusion:
\nAdenocarcinoma, lung origin.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 86<\/strong>
\nPeritoneal effusion: Adenocarcinoma, lung origin. 60x<\/div>\n<\/div>\n
Figure 86<\/strong>
\nPeritoneal effusion:
\nAdenocarcinoma, lung origin.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 87<\/strong>
\nPeritoneal effusion: Adenocarcinoma, lung origin. 60x<\/div>\n<\/div>\n
Figure 87<\/strong>
\nPeritoneal effusion:
\nAdenocarcinoma, lung origin.
\n60x<\/div>\n
<\/div>\n

Figures 85-87: Peritoneal effusion: Adenocarcinoma, lung origin.<\/strong>
\nClusters of cells with classic features of adenocarcinoma. These cells were ultimately determined to be derived from a bronchogenic carcinoma.<\/p>\n

Small cell undifferentiated carcinoma is an uncommon cause of a malignant pleural effusion. The tumor cells are small and dark, and need to be differentiated from lymphoid cells. Features of small cell undifferentiated carcinoma include nuclear molding and individual cell necrosis. Immunohistochemical stains on cell block material may be necessary to confirm the diagnosis.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 88<\/strong>
\nPleural effusion: Small cell undifferentiated carcinoma, lung origin. Note small clusters of benign mesothelial cells and three larger cells from small cell undifferentiated carcinoma on the edge of one of the clusters. 60x<\/div>\n<\/div>\n
Figure 88<\/strong>
\nPleural effusion:
\nSmall cell undifferentiated carcinoma, lung origin. Note small clusters of benign mesothelial cells and three larger cells from small cell undifferentiated carcinoma on the edge of one of the clusters.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 89<\/strong>
\nPleural effusion: Small cell undifferentiated carcinoma, lung origin. Nuclei have small nucleoli and often a salt and pepper look to the chromatin. Cytoplasm is scant. 60x<\/div>\n<\/div>\n
Figure 89<\/strong>
\nPleural effusion:
\nSmall cell undifferentiated carcinoma, lung origin. Nuclei have small nucleoli and often a salt and pepper look to the chromatin. Cytoplasm is scant.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 90<\/strong>
\nPleural effusion: Small cell undifferentiated carcinoma, lung origin. Cells of small cell undifferentiated carcinoma are discohesive and can appear singly. Note necrotic background. 60x<\/div>\n<\/div>\n
Figure 90<\/strong>
\nPleural effusion:
\nSmall cell undifferentiated carcinoma, lung origin. Cells of small cell undifferentiated carcinoma are discohesive and can appear singly. Note necrotic background.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 91<\/strong>
\nPleural effusion: Small cell undifferentiated carcinoma, lung origin. 20x<\/div>\n<\/div>\n
Figure 91<\/strong>
\nPleural effusion:
\nSmall cell undifferentiated carcinoma, lung origin.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 92<\/strong>
\nPleural effusion: Small cell undifferentiated carcinoma, lung origin. 40x<\/div>\n<\/div>\n
Figure 92<\/strong>
\nPleural effusion:
\nSmall cell undifferentiated carcinoma, lung origin.
\n40x<\/div>\n<\/div>\n
<\/div>\n

Figures 91-92: Pleural effusion: Small cell undifferentiated carcinoma, lung origin.<\/strong>
\nSmall dark cells of small cell undifferentiated carcinoma appearing singly and in small groups. Note the nuclear molding.[\/vc_column_text][vc_column_text el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row 0=””][vc_column 0=”” of<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":1947,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-1991","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/1991","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=1991"}],"version-history":[{"count":0,"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/1991\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/1947"}],"wp:attachment":[{"href":"https:\/\/stage.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=1991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}