{"id":2068,"date":"2017-07-31T19:28:38","date_gmt":"2017-07-31T19:28:38","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/negative-effusions\/"},"modified":"2025-02-10T20:04:36","modified_gmt":"2025-02-10T20:04:36","slug":"negative-effusions","status":"publish","type":"page","link":"https:\/\/stage.cytologystuff.com\/zh-hans\/non-gyn-atlas\/negative-effusions\/","title":{"rendered":"Negative Effusions"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Negative Effusions” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

NEGATIVE EFFUSIONS<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 1<\/strong>
\nPleural effusion:
\nBenign mesothelial cells 20X<\/div>\n<\/div>\n
Figure 1
\n<\/strong>Pleural effusion:
\nBenign mesothelial cells
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 2<\/strong>
\nPleural effusion:
\nBenign mesothelial cells 40X<\/div>\n<\/div>\n
Figure 2
\n<\/strong>Pleural effusion:
\nBenign mesothelial cells
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 3
\n<\/strong>Pleural effusion: Benign mesothelial cells 60X<\/div>\n<\/div>\n
Figure 3<\/strong>
\nPleural effusion:
\nBenign mesothelial cells
\n60X<\/div>\n
<\/div>\n

Figures 1-3 – Pleural effusion: Benign mesothelial cells.<\/strong>
\nSheets of benign mesothelial cells are often smaller than 12 cells, but may sometimes be composed of upwards of 50 cells. In these photomicrographs, the even dispersal of uniform cells, with regular nuclei, delicate nuclear membranes and small round nucleoli signal the benign nature of these cells.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 4<\/strong>
\nPleural effusion: Reactive mesothelial cells. 60X<\/div>\n<\/div>\n
Figure 4
\n<\/strong>Pleural effusion:
\nReactive mesothelial cells.
\n60X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 5<\/strong>
\nPleural effusion: Reactive mesothelial cells. 60x<\/div>\n<\/div>\n
Figure 5
\n<\/strong> Pleural effusion:
\nReactive mesothelial cells.
\n60x<\/div>\n
<\/div>\n

Figs 4-5: Pleural effusion: Reactive mesothelial cells.<\/strong>
\nUnder conditions of an inflammatory process, mesothelial cells are increased in number, can exhibit a wide range of sizes, and may be multinucleated. The keys to diagnosis involve (1) applying individual criteria of benignity and (2) establishing the presence of an uninterrupted continuum of sizes from small to very large. Note enlarged nuclei, small multiple nucleoli, and spaces between adjacent cells, so called “windows.” Inflammatory cells are present in the background.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 6<\/strong>
\nPeritoneal effusion: Reactive mesothelial cells. 60X<\/div>\n<\/div>\n
Figure 6
\n<\/strong>Peritoneal effusion:
\nReactive mesothelial cells.
\n60X<\/div>\n
<\/div>\n

Like pleural effusion, mesothelial cells in peritoneal effusions may exhibit a range of cell sizes. Mesothelial cells may be admixed with inflammatory cells and histiocytes.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 7<\/strong>
\nPeritoneal effusion: Benign. 60X<\/div>\n<\/div>\n
Figure 7
\n<\/strong> Peritoneal effusion:
\nBenign.
\n60X<\/div>\n
<\/div>\n

This sheet of mesothelial cells exhibits moderate cohesion. Nuclei are uniform among cells in the group. Nuclear membranes are thin and delicate and nucleoli are small round and uniform.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 8<\/strong>
\nPeritoneal effusion: Reactive mesothelial cells. 60X<\/div>\n<\/div>\n
Figure 8
\n<\/strong> Peritoneal effusion:
\nReactive mesothelial cells.
\n60X<\/div>\n
<\/div>\n

Peritoneal effusion showing mild cellular anisocytosis as a reactive process.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 9<\/strong>
\nPleural effusion: Arifacts. 20X<\/div>\n<\/div>\n
Figure 9
\n<\/strong> Pleural effusion:
\nArtifacts.
\n20X<\/div>\n
<\/div>\n

Fibers from materials used for collection or specimen processing may be noted in body effusions from any site.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 10<\/strong>
\nPericardial effusion: Benign mesothelial cells. 20X<\/div>\n<\/div>\n
Figure 10
\n<\/strong>Pericardial effusion:
\nBenign mesothelial cells.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 11<\/strong>
\nPericardial effusion: Benign mesothelial cells. 40X<\/div>\n<\/div>\n
Figure 11
\n<\/strong> Pericardial effusion:
\nBenign mesothelial cells.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 12
\n<\/strong>Pericardial effusion: Benign mesothelial cells. 60X<\/div>\n<\/div>\n
Figure 12
\n<\/strong>
\nPericardial effusion:
\nBenign mesothelial cells.
\n60X<\/div>\n<\/div>\n
<\/div>\n

Figures 10-12: Pericardial effusion Benign mesothelial cells.<\/strong>
\nPericardiocentesis may yield sheets of benign mesothelial cells similar to those found in other body cavity effusions. The etiology of pericardial effusions is more likely to be infectious (viral), autoimmune, inflammatory (myocardial infarction) or reactive (uremia). Tumor, especially lung, may also invade the pericardium.[\/vc_column_text][vc_column_text css=”.vc_custom_1500390293825{margin-top: 30px !important;}” el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

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